MPEG‑G at the Human Genome Meeting 2026 in Athens

GenomSys joined the international genomics community at the Human Genome Meeting 2026 in Athens to present the latest developments around the ISO/IEC 23092 MPEG‑G standard and the production tooling that surrounds it.

The ISO/IEC 23092 MPEG‑G standard

MPEG‑G is the joint ISO/IEC standard for the representation, compression and transport of genomic information. It was designed from the ground up to handle the scale of modern sequencing: a whole-genome sample compressed to a fraction of its original size, structured so that downstream applications can read only the slices they need without re-decoding the full file.

Delivering MPEG‑G solutions

GenomSys’ presentation walked through the full pipeline now in production:

• GVA — Genome Variant Analyzer: variant calling and annotation against MPEG‑G–encoded references, with clinical-grade reporting.
• GBT — Genome Blood Typer: blood-group antigen prediction from short-read data, used in transfusion and immunohaematology settings.
• GenomYou: a mobile companion app that lets individuals carry an encrypted copy of their genome and authorise specific analyses on demand.
• MPEG‑G Browser: a viewer for inspecting MPEG‑G archives at the byte-stream level.

Joint Labs with IIT

A significant share of GenomSys’ applied research now runs out of the Joint Labs with Istituto Italiano di Tecnologia (IIT), where teams work on next-generation compression, graph-genome representation and privacy-preserving analytics on top of the MPEG‑G base layer.

The Athens meeting closed with a working session on how the standard can underpin federated genomic data networks across European reference centres.