Around 83% smaller than BAM
A full whole-genome NovaSeq 6000 BAM (~76 GB), with all auxiliary fields, transcodes losslessly at ≈6× (~83% less) — up to ~90% (~10×) on lighter data, and 2.2× faster with the latest transcoder.
GMS · GenomSys MPEG‑G Suite · SDK & CLI
High-performance processing, native to MPEG‑G
The tool suite that brings the ISO/IEC 23092 standard to your genomic workflow — convert, compress, and process FASTQ / BAM / CRAM / MPEG‑G under one syntax, with sequencer-to-clinic interoperability built in.
- 12×
- compression vs raw FASTQ
- <1s
- selective access
- 4
- formats — FASTQ / BAM / CRAM / MPEG‑G
- 2
- platforms — Linux / Windows
Why it matters
One format, end to end
The tool suite consolidates raw and aligned sequencing data, genome assemblies, and metadata into a single highly compressed file — and integrates with the GenomSys secondary-analysis module for streamlined compression, upload, and processing.
Selective access
Reach any genomic interval in sub-second time without decompressing the whole file. ≥89% less access time vs. legacy.
Lossless transcoding
Round-trip FASTQ ⇆ BAM ⇆ CRAM ⇆ MPEG‑G with no data loss. Drop it into existing pipelines without rewriting.
One unified syntax
Reads, alignments, references, and metadata all live in the same file with full data integrity — no more multi-file coordination.
Built-in privacy
Native encryption, audit-trail metadata, and precise role-based access control — security baked into the format, not bolted on.
Sequencer-to-clinic
Connect directly to sequencer output. Skip the preprocessing step that used to gate every clinical pipeline.
How it works
A drop-in CLI + SDK
Available as a command-line tool and a programmatic library. The on-homepage console is a faithful preview — every command shown there is a real tool suite operation.
Compress
mpegg compress sample.fastq.gz
Lossless conversion to MPEG‑G with progress and a per-file size report.
Transcode
mpegg transcode --to bam sample.mgb
Bidirectional FASTQ / BAM / CRAM / MPEG‑G — fits existing pipelines.
Access
mpegg access --region chr17:43044295-43125483
Sub-second random access to any interval, no need to decompress the whole file.
Platforms & formats
Fits where your data already lives
Runs on Linux and Windows. Ingests every common genomic format. Outputs MPEG‑G files that downstream tools (GVD, Hemotyper, your in-house pipelines) can read natively.
Linux
x86_64 and ARM64. Container-friendly. Compatible with the major bioinformatics distros (Ubuntu, RHEL, Debian).
Windows
Win10 / Win11 (64-bit). Same CLI surface as the Linux build.
Input formats
FASTQ (raw + gzipped), BAM, CRAM, SAM, MPEG‑G. Read groups and headers preserved through transcoding.
Output formats
MPEG‑G (native), BAM, CRAM, FASTQ. Variant calls go to VCF via the GenomSys secondary-analysis module.
Who it's for
Built for people who run pipelines
Bioinformatics engineers, lab IT, sequencing-service providers, and clinical-pipeline teams — anyone who pays the storage / transfer / re-processing tax that legacy formats charge.
Sequencing services
Compress at the source. Deliver MPEG‑G to customers and slash both storage and bandwidth costs.
Clinical laboratories
Cut turnaround time. Direct-from-sequencer ingestion means no preprocessing bottleneck before variant calling.
Bioinformatics teams
Drop into Snakemake / Nextflow workflows. Lossless transcoding means you don't have to migrate everything at once.
Research consortia
Standardise the format across centres. ISO/IEC 23092 is the only open international standard for genomic data — interoperability without lock-in.